# S3E62 Cube chatShaala: Exploring new ways of Learning
**URL:** https://metastudio.org/t/s3e62-cube-chatshaala-exploring-new-ways-of-learning/10573
**Category:** Events
**Created:** [January 8, 2021, 7:11pm UTC](https://metastudio.org/t/s3e62-cube-chatshaala-exploring-new-ways-of-learning/10573 "2021-01-08T19:11:54Z")
**Posts on this page:** 4
**Page:** 1
### Author:  [@KiranKalakotiR](https://metastudio.org/u/KiranKalakotiR)
#### Post date: [January 8, 2021, 7:11pm UTC](https://metastudio.org/t/s3e62-cube-chatshaala-exploring-new-ways-of-learning/10573/1 "2021-01-08T19:11:54Z")
**Meeting URL**
[webinar.hbcse.tifr.res.in](https://webinar.hbcse.tifr.res.in/b/kir-vgc-6jf)
### [HBCSE Webinar](https://webinar.hbcse.tifr.res.in/b/kir-vgc-6jf)
A front-end for HBCSE web conferencing server. You can create your own rooms to host sessions, or join others using a short and convenient link.
Please click on the **HBCSE Webinar** above to join the **CUBE ChatShaala**
**Timing:5.30 pm to 9.30 pm**
**As we do it daily, CUBE chatShaala will be starting at 5.30 pm and as a continuation of it, from 8.30 pm, there will be NAIL REGENERATION WORKSHOP today in CUBE chatShaala.**
Looking forward to your participation.
Thanks
---
### Author:  [@drishtantmkawale](https://metastudio.org/u/drishtantmkawale)
#### Post date: [January 9, 2021, 4:37pm UTC](https://metastudio.org/t/s3e62-cube-chatshaala-exploring-new-ways-of-learning/10573/2 "2021-01-09T16:37:26Z")
**CUBE ChatShaala on 9th January 2021**
**34 CUBists** from **26 Centres** had joined the webinar
[Map](https://www.google.com/maps/d/u/0/edit?mid=1d7ByQb5VZBH9vSyvsqhm6pvCRrJsdDR8&usp=sharing)
**ANDHRA PRADESH**
Nellore: Tejasree
**BIHAR**
Sitamarhi: Anamika Singh
Patna: Kshipra
**DELHI**
AND College: Aastha Ahuja
Garima Kalakoti
Dyal Singh College: Dr P. Chitralekha
**JHARKHAND**
Morabadi, Ranchi: Rechel Tirkey
**KARNATAKA**
Bangalore: Shama Sayyed
**KERALA**
Kozhikode: Arunima
The Cochin College, Ernakulam: Ashikha Farzana, Bhavya, Devika Devanath, Manjula Bhat, Sumayya Parveen
Thriprayar, Thrissur: Aswathy Suresh
Kandassankadavu: Lakshmy PJ
Palakkad: Neeraja Nair, Sukanya P
Thanniam, Thrissur: Sidhy PP
**MAHARASHTRA**
South Bombay: Arunan MC
Thane: Anshu Kadam, Hitesh Pareek
Nerul: Drishtant M Kawale
HBCSE, Mumbai: DP
Mumbai: Kaninika Ghosh
Powai: Lydia Mathew
Mulund, Mumbai: Omkar Badnale, Priti Kanade
Mira Road, Mumbai: Sana Jalili
Panvel, Navi Mumbai: Shraddha Sonawane
**UTTAR PRADESH**
Kanpur: Hina Mudgal
Moradabad: Kiran Yadav
**WEST BENGAL**
Kolkata: Batul Pipewala, Sukriti Maity
---
### Author:  [@KiranKalakotiR](https://metastudio.org/u/KiranKalakotiR)
#### Post date: [January 9, 2021, 5:54pm UTC](https://metastudio.org/t/s3e62-cube-chatshaala-exploring-new-ways-of-learning/10573/3 "2021-01-09T17:54:34Z")
**09th January 2021**
Whiteboard screenshots of Cube chatShaala..
Interesting Facts related to Nail growth study and Nail Regeneration study…
What’s the difference in between **Growth** and **Regeneration**?.. How do Nails grow?..
Planaria was taken as an example in order to define what’s the Regeneration?..
**INTERESTING AND AMAZING**
Left side drawing shows the photo of the finger Nail with the Mark was taken on **10th December 2020** and also after 27 Days that’s on **06th Jan 2021**.
It has been shown that Marked has moved and the Gap was measured **5mm**
What’s does that tells us?. Does Nail have grown or have regenerated?..
What would happen when the Whole Nail get off or uprooted from the finger?..
Does that Nail Regenerate?..
**Are there any stem cells/Nail stem cells?..**
YES THERE ARE NAIL STEM CELLS IN THE NAIL BED.
This we could say by reffering an amazing Reference (References link will be posted) shared by Kaninika which enabled us to understand that yes Nail bed has Nails
stem cells and Stem cell has the ability to either self renew or specialized or Differentiated.
**But what are the Stem cells?. Can any divided cell be called as Stem cell?..**
Stem cells are the dividing cell and they are the undifferentiated cells…
Further the discussion went on what’s the difference among **Wound Healing, Regeneration and Cancer**
Amazing input given by Batul is that Cancer can be connected to Wound healing as if there’s wound healing then cell will stop dividing…(Reference link will be shared)..
How the Nail Growth study is connected to this Amazing Nail Regeneration study?..
---
### Author:  [@KiranKalakotiR](https://metastudio.org/u/KiranKalakotiR)
#### Post date: [January 9, 2021, 5:58pm UTC](https://metastudio.org/t/s3e62-cube-chatshaala-exploring-new-ways-of-learning/10573/4 "2021-01-09T17:58:02Z")
**References shared during the discussion**
**1. PNAS**
[https://www.researchgate.net/publication/266581292\_Bifunctional\_ectodermal\_stem\_cells\_around\_the\_nail\_display\_dual\_fate\_homeostasis\_and\_adaptive\_wounding\_response\_toward\_nail\_regeneration](https://www.researchgate.net/publication/266581292_Bifunctional_ectodermal_stem_cells_around_the_nail_display_dual_fate_homeostasis_and_adaptive_wounding_response_toward_nail_regeneration)
**A team of researchers has identified a new population of nail stem cells, which have the ability to either self-renew or undergo specialization or differentiation into multiple tissues.**
Under normal circumstances, the stem cells contribute to the growth of both the nails and the adjacent skin. However, if the nail is injured or lost, a protein called “Bone Morphogenic Protein,” or BMP, signals to the stem cells to shift their function exclusively to nail repair.
**Science Daily**
[https://www.sciencedaily.com/releases/2014/11/141121102922.htm#:~:text=A%20team%20of%20researchers%20has,or%20differentiation%20into%20multiple%20tissues.&text=Under%20normal%20circumstances%2C%20the%20stem,nails%20and%20the%20adjacent%20skin](https://www.sciencedaily.com/releases/2014/11/141121102922.htm#:~:text=A%20team%20of%20researchers%20has,or%20differentiation%20into%20multiple%20tissues.&text=Under%20normal%20circumstances%2C%20the%20stem,nails%20and%20the%20adjacent%20skin).
**2. BMP signaling in skeletal system**. BMPs play a crucial role in bone and cartilage formation, providing the namesake for this family of proteins, [https://www.google.com/search?client=firefox-b-d&q=BMP+protein+role](https://www.google.com/search?client=firefox-b-d&q=BMP+protein+role)
**3. Wnt activation in nail epithelium couples nail growth to digit regeneration**
[https://pubmed.ncbi.nlm.nih.gov/23760480/](https://pubmed.ncbi.nlm.nih.gov/23760480/)
**4. Nail Growth Evaluation and Factors Affecting Nail Growth**
[https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-32383-1\_121](https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-32383-1_121)
**5**.[https://www.livescience.com/65277-why-fingernails-keep-growing.html](https://www.livescience.com/65277-why-fingernails-keep-growing.html)
**As keratin cells form at the root, they’re slowly pushed forward by newly-formed cells jostling for space behind them**. Edged out from beneath the skin and into the open, the older cells flatten and harden to form the tough shield of the nail plate. “Continuous division of matrix cells pushes the nail plate forward over the nail bed at a rate of about 3 millimeters [0.1 inches] per month for fingernails, and 1 millimeter [0.04 inches] per month for toenails,” said Amanda Meyer, a lecturer in human anatomy at the University of Western Australia