Combined summary of all the CUBists who gave a summary of 3rd June webinar…for all those who missed out the summary.
[03/06, 10:54 pm] Prathamesh:
Summary — CUBE Webinar , Wednesday 3rd of June, 2020
Today’s discussion was based on viruses. The discussion was started as I have raised the question that how the first person got infected with the dengue virus; i.e. if we search for the cycle of the dengue virus, it starts from an human who is infected by the dengue virus and when the aedes aegypti i.e. the species of mosquito which is capable to carry dengue virus bites that infected person , these mosquitoes carry these virus in their salivary glands and then it spreads to the other person. So like this the discussion started and then Ashutosh connected this dengue virus with currently spreading coronavirus and we further discussed on this topic , that how the first person of this covid would got infected with this virus . So Rahul gave me some informative clues about viral transmission and structure of virus. Saida and others also joined and discussed on the raised question . As virus contains a protein coat and inside it there is DNA or RNA present . So we thought that covid is because of bats and this virus has been mutated in the bats and at last it was cleared that the first person of covid eould be infected by the mutated virus in the bats as in china people sells and consumes the bat .
So we reached at that point of coronavirus and further this coronavirus is transmitted through human to human , but the question of dengue remained unsolved may be because I was not able to connect the links given by Arunan sir and Rahul or may be some another reason .
But then too, I will think and search on it, that how the first person got infected with this dengue virus.
We all should search about it and discuss on this question and put forward our thoughts.
Thank you:blush:
[03/06, 11:48 pm] @khushdeep :
In today’s webinar, there was a discussion on the Corona Virus.
We were discussing that how did the virus got transferred from bats to humans?
My question here is,
Did they eat the bat raw or they cooked it?
If they would’ve cooked the bat, then the virus would’ve got killed there itself.
How did it transmit then?
@ Arunan Sir @drishtantmkawale @Prathamesh Elph CUBE, Lydia, @KiranKalakotiR and others member…
[04/06, 12:34 am] Prathamesh:
Mutation is not a sudden change, it takes years to get mutate and so now it would be mutated at that level where it can replicate in humans and spread the disease
And another reason for it can be the dormant state of a virus i.e. to undergo dormancy until the specific conditions or suitable environment is available
[04/06, 10:13 am] @Hinaiqbal_Mudgal :
Last evening s ROOM WEBINAR discussion DT 3.06.20.
RAHUL PUT UP STRONG ASSERTIVE QUESTIONS…
How viruses who live in animals ,like bats, cats, or dogs, have started INFECTING HUMANS OR AFFECTING HUMANS
WHAT COULD HAVE CAUSED THIS INFECTING/ AFFECTING CHANGE ?
IS IT MUTATION?
CUBIST SAIDA MENTIONED RANDOM MUTATION,
HOW DID THIS VIRUS FIRST BECOME ACTIVE IN HUMANS.
TERMS LIKE DORMANCY, LYSOGENIC, RANDOM MUTATION WERE DISCUSSED…
IT WAS A STEAMING FLOW OF ANALYSTS, BIOLOGIST. WHO SHARED THEIR VIEW IN THE SUBJECT.
***INDEED SARS. COVID - 19, MERS, BIRD FLU, SWINE FLU ARE THEY VARIANTS??? MUTANTS??
WHAT HAS CAUSED THIS SPECIATION 
@ hina cube kanpur
[04/06, 11:03 am] @saida786110 :
Summary of yesterday’s discussion
@Prathamesh Suryavanshi questioned how does dengue spread in first human
and to answer that question @Aashu Sir tried to relate it with covid-19 how did that virus started affecting human? @Rahul kushwaha added this virus was in bats or some other mammals
Is it that one day decides to affect humans?
several cubist answer it to be mutation. mutation must have occurred in covid-19 virus such that the outer protein is transformed which helped the virus to get inside human cells
so in the case of covid-19 the virus was supposing in bats and it got muted and when came in contact with humans it started to affect humans. so earlier when humans were in contact with bats the protein of this virus was not mutated as such that it could affect humans. but then the question arose where did the mutation took place? probably in bats as the virus was living inside the bats cells but what happens in the case of dengue virus. because there mosquito is just a carrier. so is it that the virus would have remain dormant until human life? certainly not @Prathamesh Suryavanshi added that even monkeys were affected by dengue virus so that could be a possibility that this virus got mutated in monkeys and and with the help of mosquitoes got transmitted to humans and started affecting humans.
@ Arunan Sir connecting it to drosophila work done by cubist Lydia and @yash_sheregare. Lydia and Yash sheregare with several other cubist want to compare CsBz drosophila melanogaster cultured in labs for more than 60 years to drosophila melanogaster found in native.
Lydia added that they are looking at the olfaction of the flies and expecting different kinds of olfaction in CsBz flies. meaning flies with good olfaction moderate olfaction not so good olfaction where as in the nature they will find flies with good olfaction because of natural selection
@Hinaiqbal_Mudgal added that in CsBz flies which are cultured in lab for more than 60 years if mutation must have occurred in it, won’t be naturally selected because the environment in the bottle is such that the food is already present at all times so the flies with good olfaction will also survive and flies with weak olfaction will also survive
[04/06, 1:42 pm] @magpie :
Take away points w.r.t Context to Curriculum
Yesterday’s Causerie where Cubist Rahul Kushawa from Delhi steered the causerie with Suryavanshi ,Saida and other cubists on how did the first human get infected with dengue or Covid.
- We are exposed to microbes all the time from animals birds around us just as humans they shed their virus through bites,droppings,feathers,animals sneezing, physical handling etc.
- We develop an infection when the virus/bacteria multiplies in our body.
- We develop a disease when the viral/bacterial multiplication is not controlled effectively by our immune system.
- To gain entry into our cells the pathogen has to cross the cell membrane. There are receptors on the membrane made of glycoproteins binding to which can help it to enter.
- The Covid 19 virus has a mutation in its spike protein which helps it fit snugly to the ACE 2 receptor protein, which helps it enter our cells easily.
- How do we know there has been a mutation by comparing genetic sequences with other viruses of Coronavirus family.
Causerie is moderated by Dr Arunan